The Hitchhiker's Guide to Virotherapy
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چکیده
منابع مشابه
The Hitchhikers' Guide to Google
The web is big. Really big. This is good because the Web now encompasses the entire history, culture, science, and achievements of the human race, not to mention JPEGs of every romantically eligible member of that race under the age of 35. This is bad because it is now too big to find anything. The ‘Hitch-Hikers Guide to Google’ is a collection of patterns that will be your guide through the In...
متن کاملThe Hitchhiker's Guide to Virotherapy
1 In contrast to most other cancer therapies, early research with oncolytic viruses (OV) tended to use direct or intratumoural routes of administration, initially motivated by concerns that the major limitation of intravenous delivery would be immune attack against the viruses, whether by complement, cytokine or most critically neutralising antibodies. Even in the absence of preformed circulati...
متن کاملHitchhikers Get Around
Previous studies have shown that hitchhiking in standard GAs can cause premature convergence. In this study we show that hitchhiking also occurs in adaptive operators, specifically, selective crossover an adaptive recombination operator. We compare selective crossover with uniform crossover (a highly disruptive operator) and show that although selective crossover favours hitchhikers more than u...
متن کاملOncolytic virotherapy.
Oncolytic virotherapy is an emerging technology that uses engineered viruses to treat malignancies. Viruses can be designed with biological specificity to infect cancerous cells preferentially, and to replicate in these cells exclusively. Malignant cells may be killed directly by overwhelming viral infection and lysis, which releases additional viral particles to infect neighboring cells and di...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2012
ISSN: 1949-2553
DOI: 10.18632/oncotarget.627